1.0LETEhttps://lete.unimi.it/en/rich600338<blockquote class="wp-embedded-content" data-secret="hiZFvHLGUP"><a href="https://lete.unimi.it/en/research-and-publications/environment-exposome-and-epigenetics/">Environment, exposome and epigenetics: the molecular processes mediating risk, adaptation and resilience</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://lete.unimi.it/en/research-and-publications/environment-exposome-and-epigenetics/embed/#?secret=hiZFvHLGUP" width="600" height="338" title="“Environment, exposome and epigenetics: the molecular processes mediating risk, adaptation and resilience” — LETE" data-secret="hiZFvHLGUP" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); /* ]]> */ </script> Introduction to epigenetic mechanisms Epigenetics encompasses the set of mechanisms that modulate gene expression without altering the DNA sequence. These processes include DNA methylation, histone modifications, chromatin remodeling, regulation by non-coding RNAs (such as microRNAs), and signaling mediated by extracellular vesicles (EVs). In particular: DNA methylation stably regulates transcriptional accessibility and can be altered by […]